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THE DOYLE GROUP

Contributing new approaches to chemical synthesis and catalysis by embracing diverse skills and perspectives, and by building a research culture that enables everyone to develop to their highest potential.

Our Team

The Doyle lab is committed to fostering an inclusive and equitable environment in our laboratory, where all members have the opportunity to reach their highest potential as scientists and people. We believe that a diversity of skills, perspectives, and experiences is critical to the success of our program and constitutes our greatest strength as a group. We welcome and value researchers of any race, color, religion, national origin, gender identity, sexual orientation, physical ability, socioeconomic status, age and more. Our goal is to create and maintain a culture where everyone feels they belong and can flourish, through tailored mentorship, interdisciplinary learning, and a collaborative atmosphere. We are committed to being leaders within the scientific community in promoting these values of inclusivity and equity.

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Latest News

Stay tuned for the latest Doyle lab happenings, publications, and group milestones.

July 11th, 2020|Thesis Defense|

Mia Borden, PhD. On June 22, Mia gave an outstanding final public oral to the department on her work in the Doyle Lab, which focused on asymmetric Ni-catalyzed cross-couplings! She recently headed south to UNC Chapel Hill, where she will

June 25th, 2020|General|

Jesús Estrada: Chem PhD, Merck Scientist, “Dreamer”. In a recent Princeton Chemistry Alumni Spotlight, Doyle Lab graduate Jesús Estrada, Ph.D. ‘19, reflected on the importance of the DACA program in allowing him to achieve his educational goals and become a Senior

May 16th, 2020|Publication|

Nucleophilic (Radio)Fluorination of Redox-Active Esters via Radical-Polar Crossover Enabled by Photoredox Catalysis. Eric and John’s work in collaboration with BMS on a redox-neutral method for nucleophilic fluorination of phthalimide esters was just published in JACS (check it out here)! Congrats on completing

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Culture

When the reactions are quenched and the hoods are closed, the Doyle lab enjoys spending time outside and around town, whether playing some pickup soccer or enjoying a good meal together. Check out some of our lab adventures, including our group retreats!

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Research

The Doyle lab conducts research at the interface of organic, organometallic, physical organic, and computational chemistry. Our goal is to address unsolved problems in organic synthesis through the development of catalysts, catalytic reactions, and synthetic methods. We apply mechanistic and computer-assisted techniques to the analysis of these reactions in order to uncover general principles that can guide the design of improved catalysts and the discovery of new reactions. Learn more about our research programs here:

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Recent Publications

Check out our most recent publications. Click “learn more” for the complete list.

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Affiliates

The Doyle Lab is a founding member of two multi-institutional centers that aim to collaboratively address challenges in the field of catalysis. BioInspired Light Escalated Chemistry or BioLEC is an Energy Frontier Research Center aimed to employ advances in photochemistry to enable photoinduced cross-coupling reactions; Center for Computer Assisted Synthesis or C-CAS affords a platform to collaboratively tackle challenges in complex molecule synthesis such as reaction optimization and predicting reactivity and selectivity using data-driven methods.

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